Author contributions Mahmoud Hussein Hadwan (Conceptualization [equal], Data curation [equal], Formal analysis [equal], Funding acquisition [equal], Investigation [equal], Methodology [equal], Project administration [equal], Resources [equal], Software [equal], Supervision [equal], Validation [equal], Visualization [equal], Writingoriginal draft [equal], and Writingreview & editing [equal]), Abbas Ali Mohammed (Data curation [equal], Investigation [equal], Methodology [equal], Software [equal], and Writingreview & editing [equal]), Saeed Najavand (Data curation [equal], Project administration [equal], Resources [equal], Software [equal], Supervision [equal], Investigation [equal], Methodology [equal], and Writingreview & editing [equal]), Roaa Altaee (Investigation [equal], Methodology [equal], Validation [equal], and Writingreview & editing [equal]), and Asad Hadwan (Data curation [equal], Formal analysis [equal], Investigation [equal], Methodology [equal], Validation [equal], and Writingreview & editing [equal]) Conflicts of interest None declared

Conversely, a target-trial emulation found small and variable cardiovascular differences between the two agents, though both outperformed non-incretin therapies (16)
Henry Meds integrates regular clinical visits, labs (lipid panels, glucose, renal function), and provider-monitored dose titration, reducing gaps in adverse event detection
Insulin resistance at baseline also plays a rolepatients with higher starting insulin levels often see faster initial results because semaglutide rapidly improves insulin sensitivity
Because GLP-1 therapy tackles underlying biological factors contributing to weight gain, it offers a more sustainable solution than traditional weight loss methods
However, the ban on compounded semaglutide will also limit access to a medication that many people rely on